Used primarily as a reagent in organic synthesis, this compound is effective for introducing the trimethylacetyl (pivaloyl) group into molecules. It is commonly employed in the preparation of pivaloyl-protected alcohols and amines, which serve as intermediates in pharmaceutical and agrochemical manufacturing. Its steric bulk helps reduce unwanted side reactions, making it valuable in selective acylations. It also finds use in the production of dyes, perfumes, and specialty esters due to its ability to form stable derivatives. In research laboratories, it acts as a dehydrating agent and derivatizing agent for analytical techniques.