3-(Trimethylsilyl)propargyl bromide

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Reagent Code: #239894
label
Alias 3-(trimethylsilyl)proglyglyceryl bromide; 3-bromo-1-trimethylsilyl-1-propylene
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CAS Number 38002-45-8

science Other reagents with same CAS 38002-45-8

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 191.14 g/mol
Formula C₆H₁₁BrSi
badge Registry Numbers
MDL Number MFCD00134460
thermostat Physical Properties
Boiling Point 44-45 °C2 mm Hg(lit.)
inventory_2 Storage & Handling
Density 1.351 g/mL at 25 °C(lit.)
Storage 2~8°C

description Product Description

Used as a key reagent in organic synthesis, particularly in the formation of carbon-carbon bonds through Sonogashira and other palladium-catalyzed coupling reactions. It serves as a propargylating agent, introducing propargyl groups with a trimethylsilyl protection, which can be selectively removed to reveal terminal alkynes. This makes it valuable in the synthesis of complex molecules, including natural products and pharmaceuticals. The silyl group enhances stability and controls reactivity, allowing for selective transformations in multi-step syntheses. Commonly employed in materials science for constructing conjugated systems and functionalized alkynes used in optoelectronic materials.

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Size Availability Unit Price Quantity
inventory 1g
10-20 days ฿180.00
inventory 5g
10-20 days ฿520.00
inventory 25g
10-20 days ฿2,290.00
inventory 100g
10-20 days ฿9,080.00

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3-(Trimethylsilyl)propargyl bromide
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Used as a key reagent in organic synthesis, particularly in the formation of carbon-carbon bonds through Sonogashira and other palladium-catalyzed coupling reactions. It serves as a propargylating agent, introducing propargyl groups with a trimethylsilyl protection, which can be selectively removed to reveal terminal alkynes. This makes it valuable in the synthesis of complex molecules, including natural products and pharmaceuticals. The silyl group enhances stability and controls reactivity, allowing fo

Used as a key reagent in organic synthesis, particularly in the formation of carbon-carbon bonds through Sonogashira and other palladium-catalyzed coupling reactions. It serves as a propargylating agent, introducing propargyl groups with a trimethylsilyl protection, which can be selectively removed to reveal terminal alkynes. This makes it valuable in the synthesis of complex molecules, including natural products and pharmaceuticals. The silyl group enhances stability and controls reactivity, allowing for selective transformations in multi-step syntheses. Commonly employed in materials science for constructing conjugated systems and functionalized alkynes used in optoelectronic materials.

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