3-(Trimethylsilyl)propargyl bromide
97%
science Other reagents with same CAS 38002-45-8
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description Product Description
Used as a key reagent in organic synthesis, particularly in the formation of carbon-carbon bonds through Sonogashira and other palladium-catalyzed coupling reactions. It serves as a propargylating agent, introducing propargyl groups with a trimethylsilyl protection, which can be selectively removed to reveal terminal alkynes. This makes it valuable in the synthesis of complex molecules, including natural products and pharmaceuticals. The silyl group enhances stability and controls reactivity, allowing for selective transformations in multi-step syntheses. Commonly employed in materials science for constructing conjugated systems and functionalized alkynes used in optoelectronic materials.
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