Widely used in organic synthesis, particularly in cross-coupling reactions such as Suzuki-Miyaura and Heck reactions, enabling the construction of complex aromatic compounds. Its iodine functionality acts as a reactive site for palladium-catalyzed transformations, making it valuable in pharmaceutical and agrochemical research. The trifluoromethoxy group enhances lipophilicity and metabolic stability, which is beneficial in drug design for improving bioavailability and resistance to degradation. Commonly employed as a building block in the development of bioactive molecules and functional materials.