Nefopam is primarily used as a non-opioid analgesic, making it effective in managing moderate to severe pain. It is often prescribed for postoperative pain, musculoskeletal pain, and neuropathic pain. Its mechanism of action differs from traditional painkillers, as it inhibits the reuptake of neurotransmitters like serotonin, norepinephrine, and dopamine, providing pain relief without the risk of respiratory depression associated with opioids. Additionally, it is sometimes used in cases where opioid use is contraindicated or when patients are at risk of opioid dependency. Nefopam is also utilized in managing chronic pain conditions, offering an alternative for patients who do not respond well to conventional analgesics. Its use in cancer pain management has also been explored, particularly in combination with other pain-relieving medications.