GSK621 is primarily investigated for its potential therapeutic applications in the treatment of various diseases. It is known to act as an activator of AMP-activated protein kinase (AMPK), a key regulator of cellular energy homeostasis. This property makes it a promising candidate for addressing metabolic disorders such as type 2 diabetes and obesity, as AMPK activation helps improve glucose uptake and lipid metabolism. Additionally, GSK621 is being studied for its potential role in cancer therapy, as AMPK activation can inhibit tumor growth by regulating cell proliferation and survival pathways. Its anti-inflammatory properties are also being explored, suggesting potential applications in managing inflammatory diseases. Further research is ongoing to fully understand its efficacy and safety in these areas.