EMD638683 S-Form is primarily researched for its potential therapeutic applications, particularly in the field of metabolic disorders. It is known to act as a selective activator of AMP-activated protein kinase (AMPK), a key regulator of cellular energy homeostasis. This activation can enhance glucose uptake and fatty acid oxidation, making it a promising candidate for managing conditions like type 2 diabetes and obesity. Additionally, its role in modulating lipid metabolism suggests potential benefits in reducing cardiovascular risks associated with metabolic syndrome. Research is ongoing to explore its efficacy and safety in clinical settings.