Arg-AMS is primarily used in biochemical research as a potent inhibitor of arginyl-tRNA synthetase, an enzyme crucial for protein synthesis. By inhibiting this enzyme, Arg-AMS helps in studying the role of arginine incorporation in cellular processes and protein function. It is particularly valuable in understanding the mechanisms of aminoacyl-tRNA synthetases and their potential as targets for therapeutic interventions. Additionally, Arg-AMS is utilized in the development of antimicrobial agents, as disrupting protein synthesis in pathogens can lead to effective treatment strategies. Its application extends to cancer research, where it aids in exploring the inhibition of protein synthesis in rapidly dividing cancer cells.