1,3,4,6-Tetra-O-acetyl-2-deoxy-2-(2,2,2-trichloroethoxycarbonylamino)-β-D-glucopyranose
98%
Reagent
Code: #242978
Alias
(2S,3R,4R,5S,6R)-6-(acetoxymethyl)-3-(((2,2,2-trichloroethoxy)carbonyl)amino)tetrahydro-2H-pyran-2,4,5-triyltriacetate ester
CAS Number
122210-05-3
blur_circular Chemical Specifications
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Molecular Information
Weight
522.71 g/mol
Formula
C₁₇H₂₂Cl₃NO₁₁
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Registry Numbers
MDL Number
MFCD21608553
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Storage & Handling
Storage
-20°C, Sealed, Dry
description Product Description
Used as a key intermediate in the synthesis of complex carbohydrates and glycosaminoglycans, particularly in the preparation of heparin and heparan sulfate analogs. Its protected functional groups allow selective deprotection and coupling in oligosaccharide assembly. The trichloroethoxycarbonyl (Troc) group serves as a temporary protecting group for the amino function, which can be removed under mild reducing conditions without affecting other acetyl protections. This makes it valuable in stepwise solid-phase and solution-phase glycosylation strategies. Commonly employed in medicinal chemistry for developing anticoagulant and anti-inflammatory agents.
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