2-amino-3-[(tert-butyldiphenylsilyl)oxy]-2-methylpropan-1-ol

95%

Reagent Code: #85175
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CAS Number 280753-14-2

science Other reagents with same CAS 280753-14-2

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 343.54 g/mol
Formula C₂₀H₂₉NO₂Si
badge Registry Numbers
MDL Number MFCD30527952
inventory_2 Storage & Handling
Storage 2-8°C, inert gas, protected from light

description Product Description

This compound, 2-amino-3-[(tert-butyldiphenylsilyl)oxy]-2-methylpropan-1-ol, is a protected amino diol intermediate used in organic synthesis. The tert-butyldiphenylsilyl (TBDPS) group selectively protects the secondary hydroxyl at the 3-position, providing stability during multi-step reactions while leaving the primary alcohol at the 1-position and the amino group at the 2-position available for further transformations. This orthogonal protection strategy is valuable in the synthesis of pharmaceuticals, nucleoside analogs, sphingolipids, and other complex molecules requiring precise regiochemical control. The steric bulk of TBDPS also aids in regioselective reactions and facilitates the production of enantiomerically pure compounds.

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Test Parameter Specification
Appearance White solid
Purity 94.5-100
Infrared Spectrum Conforms to Structure
NMR Conforms to Structure

shopping_cart Available Sizes & Pricing

Size Availability Unit Price Quantity
inventory 250mg
10-20 days ฿8,300.00
inventory 1g
10-20 days ฿25,000.00

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2-amino-3-[(tert-butyldiphenylsilyl)oxy]-2-methylpropan-1-ol
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This compound, 2-amino-3-[(tert-butyldiphenylsilyl)oxy]-2-methylpropan-1-ol, is a protected amino diol intermediate used in organic synthesis. The tert-butyldiphenylsilyl (TBDPS) group selectively protects the secondary hydroxyl at the 3-position, providing stability during multi-step reactions while leaving the primary alcohol at the 1-position and the amino group at the 2-position available for further transformations. This orthogonal protection strategy is valuable in the synthesis of pharmaceuticals,

This compound, 2-amino-3-[(tert-butyldiphenylsilyl)oxy]-2-methylpropan-1-ol, is a protected amino diol intermediate used in organic synthesis. The tert-butyldiphenylsilyl (TBDPS) group selectively protects the secondary hydroxyl at the 3-position, providing stability during multi-step reactions while leaving the primary alcohol at the 1-position and the amino group at the 2-position available for further transformations. This orthogonal protection strategy is valuable in the synthesis of pharmaceuticals, nucleoside analogs, sphingolipids, and other complex molecules requiring precise regiochemical control. The steric bulk of TBDPS also aids in regioselective reactions and facilitates the production of enantiomerically pure compounds.

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