Used as a key building block in medicinal chemistry, particularly in the design of bioactive molecules and drug candidates. Its rigid, three-dimensional structure helps improve metabolic stability and binding selectivity in pharmaceuticals. Commonly employed in the development of CNS agents, enzyme inhibitors, and receptor modulators due to its ability to project substituents in defined spatial orientations. Also utilized in fragment-based drug discovery and as a scaffold in the synthesis of novel compounds with enhanced pharmacokinetic properties.