L-Homoarginine hydrochloride is widely used in biochemical research to study nitric oxide metabolism and cardiovascular health. It serves as a substrate for nitric oxide synthase, helping researchers understand its role in vascular function and potential therapeutic applications. Additionally, it is utilized in metabolic studies to investigate its effects on arginine pathways and its potential as a biomarker for cardiovascular diseases. In pharmaceutical development, it is explored for its potential to improve endothelial function and manage conditions like hypertension and heart failure. Its application extends to nutritional science, where it is studied for its role in enhancing physical performance and recovery.