This chemical is primarily used in neuroscience research as a selective and potent antagonist of NMDA (N-methyl-D-aspartate) receptors. It helps in studying the role of these receptors in synaptic plasticity, learning, and memory processes. Additionally, it is employed in experiments to understand excitotoxicity, a process linked to neuronal damage in conditions like stroke and neurodegenerative diseases. Its application extends to investigating the mechanisms of glutamate signaling in the central nervous system, providing insights into potential therapeutic targets for neurological disorders.