Used in peptide synthesis, particularly in solid-phase peptide synthesis (SPPS), where it serves as a building block for constructing peptides using the D-enantiomer of glutamic acid. The Fmoc group protects the amino group during the synthesis process, while the tert-butyl ester group protects the carboxylic acid side chain of D-glutamic acid. This allows for selective deprotection and coupling steps, enabling the precise assembly of peptide chains. It is commonly employed in the production of therapeutic peptides, research peptides, and peptidomimetics, contributing to advancements in drug development and biochemical studies. Its stability and compatibility with various reagents make it a reliable choice for complex peptide synthesis workflows.