tert-Butyl 4-aminobenzoate
98%
Reagent
Code: #143697
Alias
Tert-butyl para-aminobenzoate
CAS Number
18144-47-3
blur_circular Chemical Specifications
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Molecular Information
Weight
193.24 g/mol
Formula
C₁₁H₁₅NO₂
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Registry Numbers
MDL Number
MFCD00665790
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Physical Properties
Melting Point
108-110 °C
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Storage & Handling
Storage
Room temperature
description Product Description
tert-Butyl 4-aminobenzoate is used as an intermediate in organic synthesis, particularly in the preparation of pharmaceuticals, fine chemicals, dyes, UV absorbers, and local anesthetics such as benzocaine derivatives. It acts as a protected form of 4-aminobenzoic acid, where the carboxylic acid is esterified with a tert-butyl group, enabling selective reactions at the free amine functionality without interference from the acidic carboxyl group. The tert-butyl ester offers good stability and can be selectively deprotected under mild acidic conditions, making it valuable in multi-step syntheses requiring orthogonal protection strategies.
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