Used primarily in medical diagnostics to measure renal plasma flow. It helps assess kidney function by determining how efficiently the kidneys clear the substance from the blood. Administered intravenously, it is rapidly excreted by the kidneys through tubular secretion, making it an effective marker for evaluating effective renal plasma flow (ERPF). Due to its predictable excretion pattern, it supports the diagnosis and monitoring of kidney disorders, especially in detecting tubular dysfunction and evaluating renal blood flow in clinical settings.