Poly-L-ornithine hydrobromide is widely used in cell culture applications as a coating agent to enhance cell adhesion. It is particularly effective in promoting the attachment of neurons and other cell types to glass or plastic surfaces, making it a valuable tool in neuroscience and cell biology research. The compound is also employed in the preparation of substrates for studying cell behavior, differentiation, and growth in vitro. Additionally, it is utilized in tissue engineering to create biomimetic environments that support cell proliferation and tissue development. Its ability to improve cell attachment and stability makes it a key component in various experimental and therapeutic applications.