Z-Gly-OH is widely used in peptide synthesis as a protecting group for the amino terminus of glycine. It helps prevent unwanted reactions during the formation of peptide bonds, ensuring the synthesis proceeds efficiently. This compound is particularly valuable in solid-phase peptide synthesis (SPPS), where it aids in the stepwise assembly of peptides. Additionally, Z-Gly-OH is employed in the preparation of bioactive peptides and pharmaceutical intermediates, contributing to the development of therapeutic agents. Its stability and ease of removal under mild conditions make it a preferred choice in organic and medicinal chemistry research.