Boc-N-alpha-Methyl-O-benzyl-L-tyrosine
98%
Reagent
Code: #104829
Alias
Boc-N-methyl-O-benzyl-L-tyrosine ; N-tert-butoxycarbonyl-N-methyl-O-benzyl-L-tyrosine
CAS Number
64263-81-6
blur_circular Chemical Specifications
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Molecular Information
Weight
385.45 g/mol
Formula
C₂₂H₂₇NO₅
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Registry Numbers
MDL Number
MFCD00038755
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Storage & Handling
Storage
2~8°C
description Product Description
This compound is primarily used in peptide synthesis as a protected amino acid derivative. Its Boc (tert-butoxycarbonyl) group serves as a temporary protecting group for the amine functionality, while the benzyl group protects the hydroxyl group of tyrosine. This protection strategy allows for selective reactions during peptide chain assembly, particularly in solid-phase peptide synthesis (SPPS). It is valuable in the production of complex peptides and proteins, where precise control over amino acid coupling is essential. Additionally, it finds applications in the development of peptide-based pharmaceuticals, where modifications like N-alpha-methylation can enhance stability, bioavailability, or receptor binding affinity. Its use is also relevant in research settings for studying peptide structure-activity relationships and designing novel bioactive molecules.
format_list_bulleted Product Specification
| Test Parameter | Specification |
|---|---|
| Melting Point | 0 |
| Purity (HPLC) | 98-100 |
| Specific Rotation [A]20/D (C=1, Ethanol) | 0 |
| 300 MHz 1H NMR Spectrum | Conforms to Structure |
| Appearance | Beige Powder |
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