Used in peptide synthesis as a protected amino acid derivative, particularly in the preparation of biologically active peptides. The trimethylsilyl group acts as a protective moiety for the side chain, allowing selective reactivity during coupling steps. Its indole ring and stereochemistry make it suitable for constructing enzyme substrates or inhibitors, especially in studies involving tryptophan-containing peptides. Commonly applied in pharmaceutical research for developing peptide-based drugs with enhanced stability and specificity.