Used in biochemical research as a chiral building block for synthesizing histidine-based peptides and enzyme inhibitors. Serves as a precursor in the preparation of labeled compounds for metabolic studies and mass spectrometry. Employed in studies related to histidine metabolism, neurotransmitter regulation, and histamine pathway analysis. Also utilized in the development of pharmaceutical intermediates targeting neurological and immunological disorders. Its zwitterionic structure makes it useful in buffer systems and molecular recognition studies.