(2S,4S)-1-(((9H-Fluoren-9-yl)methoxy)carbonyl)-4-benzylpyrrolidine-2-carboxylic acid
97%
Reagent
Code: #232510
CAS Number
1334671-66-7
blur_circular Chemical Specifications
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Molecular Information
Weight
427.49 g/mol
Formula
C₂₇H₂₅NO₄
thermostat
Physical Properties
Boiling Point
628.7±48.0 °C(Predicted)
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Storage & Handling
Density
1.286±0.06 g/cm3(Predicted)
Storage
2-8°C, sealed, dry
description Product Description
Widely used in peptide synthesis, this compound serves as a chiral building block for the preparation of complex organic molecules, especially in the development of pharmaceuticals. Its structure incorporates a fluorenylmethyloxycarbonyl (Fmoc) protecting group, which is essential in solid-phase peptide synthesis due to its base-labile characteristics, allowing selective deprotection without affecting other sensitive functional groups. The pyrrolidine ring with defined stereochemistry enables control over molecular conformation, making it valuable in the design of protease inhibitors and other bioactive compounds. Its carboxylic acid functionality allows for easy coupling to amines, facilitating stepwise assembly of peptide chains. Commonly employed in medicinal chemistry research, it supports the synthesis of peptidomimetics with enhanced metabolic stability and target specificity.
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