(R)-3-((tert-Butoxycarbonyl)amino)-3-(4-(trifluoromethyl)phenyl)propanoic acid
98%
Reagent
Code: #230633
CAS Number
501015-19-6
science Other reagents with same CAS 501015-19-6
blur_circular Chemical Specifications
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Molecular Information
Weight
333.3 g/mol
Formula
C₁₅H₁₈F₃NO₄
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Registry Numbers
MDL Number
MFCD03427965
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Physical Properties
Melting Point
157 - 159 ℃
Boiling Point
432.7±45.0 ℃(Predicted)
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Storage & Handling
Density
1.269±0.06 g/cm3(Predicted)
Storage
2-8°C
description Product Description
Used as a chiral intermediate in the synthesis of pharmaceutical compounds, particularly in the development of protease inhibitors and other biologically active molecules. Its structure supports the formation of peptide-like frameworks with enhanced metabolic stability due to the presence of the trifluoromethyl group. Commonly employed in medicinal chemistry for structure-activity relationship (SAR) studies, especially in optimizing drug candidates targeting enzymes and receptors where stereochemistry plays a critical role in activity. The Boc-protected amine allows for selective deprotection and further coupling reactions in multi-step syntheses.
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