O-[2-Acetamido-4,6-O-benzylidene-2-deoxy-3-O-(2,3,4,6-tetra-O-acetyl-b-D-galactopyranosyl)-a-D-galactopyranosyl]-N-Fmoc-L-threonine allyl ester
95%
Reagent
Code: #221145
CAS Number
384346-85-4
blur_circular Chemical Specifications
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Molecular Information
Weight
1003.008 g/mol
Formula
C₅₁H₅₈N₂O₁₉
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Registry Numbers
MDL Number
MFCD30719830
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Storage & Handling
Storage
-20°C
description Product Description
Used as a glycosylated amino acid building block in solid-phase peptide synthesis, particularly for constructing complex glycopeptides with tumor-associated carbohydrate antigens. The Fmoc group allows for mild base deprotection compatible with automated synthesis, while the allyl ester protects the carboxylic acid and can be selectively removed under neutral conditions using palladium catalysts. The benzylidene and acetyl groups stabilize the sugar moiety during synthesis and can be selectively deprotected to enable further glycosylation or modification. This compound is especially valuable in the preparation of cancer vaccine candidates and glycoconjugate mimics for immunological studies.
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