Used in peptide synthesis and medicinal chemistry as a building block for constructing constrained cyclic structures. The Fmoc-protected amine allows for solid-phase peptide synthesis using standard Fmoc-strategy, while the cyclohexanone ring introduces conformational rigidity, useful for studying structure-activity relationships. The ketone group can undergo selective derivatization, such as oxime or hydrazone formation, enabling bioconjugation or the introduction of labels and functional groups. Commonly employed in the development of peptidomimetics and enzyme inhibitors where backbone cyclization or steric control is required.