Hyp9 is widely used in the development of peptide-based therapeutics due to its ability to stabilize collagen-like structures. It enhances the thermal stability of synthetic peptides, making it valuable in tissue engineering and regenerative medicine applications. Its role in promoting cell adhesion and extracellular matrix formation supports its use in biomaterials designed for wound healing and 3D cell culture systems. Additionally, Hyp9 is employed in diagnostic assays that require stable peptide conformations, particularly in detecting collagen-related disorders. Its compatibility with solid-phase peptide synthesis allows for efficient incorporation into complex molecular designs for drug discovery and biochemical research.