H-Cha-OH, also known as Cyclohexylalanine, is a non-proteinogenic amino acid widely used in peptide synthesis to incorporate a hydrophobic, bulky side chain that enhances peptide stability against enzymatic degradation and improves pharmacokinetic properties such as bioavailability and membrane permeability. It serves as a phenylalanine analog, enabling the design of bioactive peptides, enzyme inhibitors, and peptidomimetics with reduced immunogenicity and increased metabolic stability. Compatible with standard coupling reagents, it is employed in both solution-phase and solid-phase synthesis for pharmaceutical research and development.