2-(((9H-Fluoren-9-yl)methoxy)carbonyl)-6-oxodecahydroisoquinoline-3-carboxylic acid
97%
Reagent
Code: #191128
CAS Number
1403766-52-8
science Other reagents with same CAS 1403766-52-8
blur_circular Chemical Specifications
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Molecular Information
Weight
419.477 g/mol
Formula
C₂₅H₂₅NO₅
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Registry Numbers
MDL Number
MFCD23106316
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Physical Properties
Boiling Point
646.3±55.0 °C(Predicted)
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Storage & Handling
Density
1.310±0.06 g/cm3(Predicted)
Storage
Room temperature
description Product Description
Widely used in peptide synthesis as a protecting group for amines, particularly in solid-phase peptide synthesis (SPPS). The compound enables selective protection of amino groups due to its stability under basic and acidic conditions, yet it can be efficiently removed under mild basic conditions, typically using piperidine. This allows stepwise assembly of complex peptides without disturbing other functional groups. Its fluorenyl moiety provides UV detectability, facilitating reaction monitoring during synthesis. Commonly employed in the preparation of therapeutic peptides, research reagents, and biochemical probes.
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