Fmoc-PNA-A(Bhoc)-OH
≥98%(HPLC)
Reagent
Code: #189769
CAS Number
186046-82-2
blur_circular Chemical Specifications
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Molecular Information
Weight
725.76 g/mol
Formula
C₄₀H₃₅N₇O₇
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Storage & Handling
Storage
-20°C
description Product Description
Used in solid-phase peptide synthesis, this compound enables the controlled assembly of peptide nucleic acid (PNA) sequences with high fidelity. The Fmoc group allows for orthogonal protection strategies, facilitating stepwise chain elongation in automated synthesizers. The Bhoc protecting group on the adenine base prevents unwanted side reactions during coupling, ensuring clean deprotection under mild acidic conditions. Its primary application lies in the production of PNA oligomers for research in molecular biology, including gene regulation studies, antisense technology, and development of nucleic acid diagnostics. The compound is also valuable in creating PNA probes for detecting specific DNA or RNA sequences due to PNA's strong and selective binding properties.
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