Used in peptide synthesis as a chiral building block for incorporating non-natural amino acid residues into peptides. The Fmoc group allows for solid-phase synthesis using standard Fmoc-strategy protocols, enabling the construction of complex peptide sequences under mild basic conditions. The 2-chlorophenyl substituent provides steric bulk and aromatic character, which can influence peptide conformation, stability, and biological activity. Commonly applied in the development of peptidomimetics, enzyme inhibitors, and pharmaceutical research where stereochemistry and side-chain functionality play critical roles in target binding. Its (R)-configuration ensures defined stereochemical control in structure-activity relationship studies.