Fmoc-D-2-amino-4-bromo-4-pentenoic acid
98%
Reagent
Code: #188948
CAS Number
220497-92-7
blur_circular Chemical Specifications
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Storage & Handling
Storage
2-8°C
description Product Description
Used in peptide synthesis as a chiral building block for introducing constrained amino acid residues into peptides. The Fmoc group allows for solid-phase synthesis by providing orthogonal protection for the amino group, enabling stepwise assembly of peptide chains. The bromoalkene moiety serves as a reactive handle for further modification via cross-coupling reactions or as a structural mimic in bioactive peptide analogs. Its D-configuration imparts resistance to proteolytic degradation, making it useful in designing metabolically stable peptide-based therapeutics. Commonly applied in medicinal chemistry for developing enzyme inhibitors or probing structure-activity relationships in peptide receptors.
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