Used in solid-phase peptide synthesis as a chiral building block for constructing complex bioactive peptides. Its Fmoc protection allows for mild deprotection conditions, making it compatible with sensitive peptide sequences. The (2S,3S) stereochemistry is valuable for mimicking natural amino acid motifs found in protease inhibitors and other pharmacologically active peptides. Commonly employed in the synthesis of antitumor agents, antiviral drugs, and enzyme inhibitors where precise stereochemistry and side-chain functionality are critical. The hydroxy group can serve as a site for further modification or as a structural element influencing peptide conformation and stability.