Used in solid-phase peptide synthesis, this compound serves as a protected amino acid building block for incorporating N-methylated D-glutamine residues into peptide chains. Its Fmoc group allows for mild base-labile protection, compatible with standard Fmoc/tBu strategies, enabling the synthesis of complex peptides with enhanced metabolic stability and conformational constraints. Commonly applied in the development of therapeutic peptides, enzyme inhibitors, and peptidomimetics where backbone methylation improves bioavailability and resistance to proteolysis. The D-configuration contributes to increased stability and can influence receptor selectivity in bioactive peptides.