Fmoc-Phenylalaninol
98.5%
Reagent
Code: #187150
CAS Number
129397-83-7
blur_circular Chemical Specifications
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Molecular Information
Weight
373.4 g/mol
Formula
C₂₄H₂₃NO₃
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Storage & Handling
Storage
2-8°C
description Product Description
Widely used in peptide synthesis, this compound serves as a protected amino alcohol building block, enabling stepwise construction of complex peptides on solid supports. Its Fmoc group allows for mild base deprotection, compatible with a range of side-chain protecting groups. It is particularly useful in synthesizing C-terminal modified peptides, where the alcohol function can act as a precursor for further transformations or as a mimic of reduced peptide bonds. Commonly applied in the preparation of peptidomimetics and enzyme inhibitors, it supports drug discovery efforts targeting proteases and receptor ligands. Also employed in the development of labeled peptides, where the hydroxyl group can be functionalized for conjugation with fluorophores, biotin, or other probes. Its stability and selective deprotection profile make it valuable in automated and solution-phase peptide synthesis workflows.
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