Used in solid-phase peptide synthesis, this reagent enables efficient incorporation of protected amino acids by stabilizing the phosphate backbone through the aminotriester approach. It is particularly valuable in the synthesis of phosphopeptides, where it helps prevent side reactions and improves coupling efficiency. The Fmoc group allows for mild deprotection conditions, making it compatible with a wide range of side-chain protecting groups. Its application simplifies the stepwise assembly of complex peptide sequences on resin supports, enhancing purity and yield in final products. Widely adopted in research settings for drug discovery and biochemical studies involving phosphorylated peptides.