4-Chloro-Phe-OH
98%
Reagent
Code: #158321
Alias
L-4-Chlorophenylalanine; 4-Chloro-L-Phenylalanine
CAS Number
14173-39-8
blur_circular Chemical Specifications
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Molecular Information
Weight
199.63 g/mol
Formula
C₉H₁₀ClNO₂
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Registry Numbers
EC Number
238-023-5
MDL Number
MFCD00063065
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Physical Properties
Melting Point
263 °C (dec.)(lit.)
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Storage & Handling
Storage
Room temperature
description Product Description
Used in peptide synthesis, particularly in the development of bioactive peptides and pharmaceutical research. Its chlorinated aromatic side chain enhances peptide stability and influences receptor binding affinity. Commonly employed in the study of structure-activity relationships (SAR) of peptides, especially those targeting G-protein coupled receptors (GPCRs). Also utilized as an intermediate in the preparation of enzyme inhibitors and diagnostic agents. The presence of the chlorine atom allows for further functionalization via cross-coupling reactions, making it valuable in medicinal chemistry for lead optimization.
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