tert-butyl (8-methyl-1,4-dioxaspiro[4.5]decan-8-yl)carbamate
95%
science Other reagents with same CAS 792913-82-7
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description Product Description
This compound, tert-butyl (8-methyl-1,4-dioxaspiro[4.5]decan-8-yl)carbamate, serves as a dual-protected intermediate in organic synthesis. It features a tert-butoxycarbonyl (Boc) protecting group for the amine functionality and a 1,3-dioxolane acetal protecting the ketone in the underlying 4-amino-4-methylcyclohexanone structure. This dual protection enables selective manipulations in multi-step syntheses, particularly in peptide chemistry and pharmaceutical development, where it prevents unwanted reactions at the amine or carbonyl sites. The Boc group provides acid-labile stability, allowing deprotection with TFA or HCl, while the acetal is removed under aqueous acidic conditions. Its spirocyclic design facilitates the creation of structurally diverse compounds for drug discovery, APIs, and materials science.
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