Used primarily in organic synthesis as a protecting group for amines, particularly in peptide synthesis. It helps prevent unwanted reactions at the amine site during complex chemical processes. Its nitrobenzenesulfonamide component provides stability under various reaction conditions, making it suitable for multi-step synthetic routes. Additionally, it can be selectively removed under mild conditions, allowing for the controlled deprotection of amines without disrupting other functional groups in the molecule. This makes it a valuable tool in the development of pharmaceuticals and biologically active compounds.