tert-butyl (2,2-difluorospiro[2.5]octan-1-yl)carbamate
95%
Reagent
Code: #241872
blur_circular Chemical Specifications
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Molecular Information
Weight
261.15 g/mol
Formula
C₁₃H₂₁F₂NO₂
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Storage & Handling
Storage
2-8℃
description Product Description
Used as an intermediate in pharmaceutical synthesis, particularly in the development of bioactive molecules requiring spirocyclic and fluorinated motifs. The tert-butyl carbamate (Boc) group serves as a protecting group for amines, enabling selective reactions in multi-step organic syntheses. The difluorospiro[2.5]octane structure enhances metabolic stability and membrane permeability, making it valuable in medicinal chemistry for optimizing drug candidates. Commonly employed in the preparation of protease inhibitors and central nervous system agents where fluorination improves pharmacokinetic properties.
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