Tert-butyl allylcarbamate
≥95%
blur_circular Chemical Specifications
description Product Description
Tert-butyl allylcarbamate, also known as N-allyl carbamic acid tert-butyl ester or Boc-NH-allyl, is a versatile building block in organic synthesis. It features an allylamine moiety protected with a tert-butoxycarbonyl (Boc) group, which shields the amine functionality during multi-step reactions. This protection is stable under basic and nucleophilic conditions but can be selectively removed using mild acidic conditions, such as trifluoroacetic acid (TFA), to liberate the free allylamine. The allyl group enables additional orthogonal deprotection strategies or participation in palladium-catalyzed reactions like allylic substitutions. It is particularly valuable in pharmaceutical and peptide synthesis for constructing complex molecules containing allylamine units, offering high selectivity and compatibility with sensitive functional groups.
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