N-Boc-(p-tosyl)methanamine, tert-Butyl tosylmethylcarbamate, (Toluene-4-sulfonylmethyl)carbamic acid, tert-butyl ester

97%

Reagent Code: #218620
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CAS Number 433335-00-3

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 285.36 g/mol
Formula C₁₃H₁₉NO₄S
badge Registry Numbers
MDL Number MFCD09842844
thermostat Physical Properties
Melting Point 115-119 °C
Boiling Point 455.1±45.0 °C(Predicted)
inventory_2 Storage & Handling
Density 1.177±0.06 g/cm3(Predicted)
Storage Room temperature, inflatable

description Product Description

Used primarily as a protected amine intermediate in organic synthesis, particularly in the pharmaceutical and agrochemical industries. The Boc (tert-butoxycarbonyl) group provides stability under various reaction conditions while allowing for selective deprotection under mild acidic conditions. The tosyl (p-toluenesulfonyl) group enhances the stability of the methylene linker and can act as a good leaving group, enabling further functionalization such as alkylation or cross-coupling reactions. Commonly employed in multi-step syntheses of complex molecules, including active pharmaceutical ingredients (APIs), where controlled amine reactivity is essential. Its dual protection strategy makes it valuable in peptide chemistry and heterocycle formation.

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Size Availability Unit Price Quantity
inventory 1g
10-20 days ฿4,400.00

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