N-Boc-(p-tosyl)methanamine, tert-Butyl tosylmethylcarbamate, (Toluene-4-sulfonylmethyl)carbamic acid, tert-butyl ester

97%

Reagent Code: #218620
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CAS Number 433335-00-3

science Other reagents with same CAS 433335-00-3

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 285.36 g/mol
Formula C₁₃H₁₉NO₄S
badge Registry Numbers
MDL Number MFCD09842844
thermostat Physical Properties
Melting Point 115-119 °C
Boiling Point 455.1±45.0 °C(Predicted)
inventory_2 Storage & Handling
Density 1.177±0.06 g/cm3(Predicted)
Storage Room temperature, inflatable

description Product Description

Used primarily as a protected amine intermediate in organic synthesis, particularly in the pharmaceutical and agrochemical industries. The Boc (tert-butoxycarbonyl) group provides stability under various reaction conditions while allowing for selective deprotection under mild acidic conditions. The tosyl (p-toluenesulfonyl) group enhances the stability of the methylene linker and can act as a good leaving group, enabling further functionalization such as alkylation or cross-coupling reactions. Commonly employed in multi-step syntheses of complex molecules, including active pharmaceutical ingredients (APIs), where controlled amine reactivity is essential. Its dual protection strategy makes it valuable in peptide chemistry and heterocycle formation.

Available Sizes & Pricing

Size Availability Unit Price Quantity
1g
10-20 days ฿4,400.00

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N-Boc-(p-tosyl)methanamine, tert-Butyl tosylmethylcarbamate, (Toluene-4-sulfonylmethyl)carbamic acid, tert-butyl ester
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Used primarily as a protected amine intermediate in organic synthesis, particularly in the pharmaceutical and agrochemical industries. The Boc (tert-butoxycarbonyl) group provides stability under various reaction conditions while allowing for selective deprotection under mild acidic conditions. The tosyl (p-toluenesulfonyl) group enhances the stability of the methylene linker and can act as a good leaving group, enabling further functionalization such as alkylation or cross-coupling reactions. Commonly e

Used primarily as a protected amine intermediate in organic synthesis, particularly in the pharmaceutical and agrochemical industries. The Boc (tert-butoxycarbonyl) group provides stability under various reaction conditions while allowing for selective deprotection under mild acidic conditions. The tosyl (p-toluenesulfonyl) group enhances the stability of the methylene linker and can act as a good leaving group, enabling further functionalization such as alkylation or cross-coupling reactions. Commonly employed in multi-step syntheses of complex molecules, including active pharmaceutical ingredients (APIs), where controlled amine reactivity is essential. Its dual protection strategy makes it valuable in peptide chemistry and heterocycle formation.

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