N,O-Bis(trifluoroacetyl)hydroxylamine
98%
Reagent
Code: #217814
CAS Number
684-78-6
blur_circular Chemical Specifications
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Molecular Information
Weight
225.05 g/mol
Formula
C₄HF₆NO₃
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Registry Numbers
MDL Number
MFCD00013565
thermostat
Physical Properties
Melting Point
58.0-62.0°C
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Storage & Handling
Storage
2-8°C
description Product Description
Used as a highly effective reagent for the introduction of the trifluoroacetyl group in organic synthesis. It serves as a selective protecting group agent for amines and hydroxylamines due to the strong electron-withdrawing nature of the trifluoroacetyl moiety. Commonly employed in the preparation of fluorinated compounds, especially in pharmaceutical and agrochemical research where fluorine substitution enhances metabolic stability and bioavailability. Also utilized in the synthesis of hydroxylamine derivatives that act as intermediates in the formation of nitrogen-containing heterocycles. Its reactivity allows for mild reaction conditions and high yields in acylation processes.
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