1-tert-Butoxycarbonylimidazole
98%
Reagent
Code: #216834
Alias
N-Boc-imidazole
CAS Number
49761-82-2
blur_circular Chemical Specifications
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Molecular Information
Weight
168.19 g/mol
Formula
C₈H₁₂N₂O₂
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Registry Numbers
MDL Number
MFCD00014497
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Physical Properties
Melting Point
45-47 °C(lit.)
Boiling Point
147-150 °C(lit.)
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Storage & Handling
Storage
Room temperature
description Product Description
Used as a reagent for introducing the tert-butoxycarbonyl (Boc) protecting group to amines in organic synthesis. It is particularly effective in peptide synthesis where selective protection of amino groups is required. The compound reacts under mild conditions, minimizing side reactions, and is especially useful when working with sensitive substrates. It can also be employed in the protection of other nucleophiles such as alcohols and thiols. Its stability and ease of handling make it a preferred choice over more hazardous Boc-protecting agents like di-tert-butyl dicarbonate in certain applications.
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