N-(2-Aminoethyl)-2-nitrobenzenesulfonamide Hydrochloride is a specialty chemical intermediate used in organic synthesis. It contains a free primary amine on the ethyl chain and a 2-nitrobenzenesulfonamide (Nosyl) protecting group on the adjacent nitrogen, enabling orthogonal protection strategies. The free amine facilitates attachment to other molecules, while the Nosyl group can be selectively removed under mild conditions using thiols or reducing agents, avoiding interference with other functional groups. This compound is particularly valuable in peptide synthesis, pharmaceutical development, and the preparation of bioactive molecules, where precise control over amine protection and deprotection is essential. The nitro functionality also allows for further derivatization, such as reduction to an amine, enhancing its utility as a versatile building block in laboratory and industrial applications.