tert-Butyl ((1R,2S)-2-phenylcyclopropyl)carbamate
97%
Reagent
Code: #148294
CAS Number
185256-47-7
blur_circular Chemical Specifications
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Molecular Information
Weight
233.31 g/mol
Formula
C₁₄H₁₉NO₂
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Registry Numbers
MDL Number
MFCD21106315
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Physical Properties
Boiling Point
351.1±22.0°C at 760 mmHg
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Storage & Handling
Storage
2-8°C, dry seal
description Product Description
Used as an intermediate in the synthesis of pharmaceutical compounds, particularly in the development of chiral active ingredients. Its cyclopropyl structure with defined stereochemistry makes it valuable for constructing enantiomerically pure drugs, especially in central nervous system agents and cardiovascular medications. The tert-butoxycarbonyl (Boc) protecting group allows for controlled amine reactivity during multi-step syntheses, enabling selective coupling reactions in peptide-like frameworks. Commonly employed in research settings for structure-activity relationship (SAR) studies due to its rigid backbone and ability to influence metabolic stability.
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