4-(Trifluoromethyl)benzenecarboximidamide
95%
Reagent
Code: #243946
CAS Number
131472-28-1
blur_circular Chemical Specifications
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Molecular Information
Weight
188.15 g/mol
Formula
C₈H₇F₃N₂
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Storage & Handling
Storage
Room temperature
description Product Description
Used as a key intermediate in the synthesis of pharmaceuticals, particularly in the development of kinase inhibitors for cancer treatment. Its structure supports binding to enzyme active sites, enhancing selectivity and potency. Also employed in agrochemicals to improve metabolic stability and lipophilicity, aiding in better penetration and efficacy. Commonly utilized in medicinal chemistry for structure-activity relationship (SAR) studies due to the electron-withdrawing trifluoromethyl group that influences electronic and steric properties.
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