Used in pharmaceutical synthesis as a chiral intermediate for protease inhibitors, particularly in the development of antiviral drugs. Its hydroxyamide structure with a defined stereochemistry enables selective binding to enzyme active sites. Commonly employed in the preparation of inhibitors targeting hepatitis C virus (HCV) NS3/4A protease. The cyclopropyl group enhances metabolic stability and membrane permeability, improving oral bioavailability in drug candidates. Also utilized in structure-activity relationship (SAR) studies to optimize potency and selectivity in medicinal chemistry programs.