Used as a Weinreb amide reagent in organic synthesis, particularly for the controlled formation of ketones bearing the 1-(trifluoromethyl)cyclopropanecarbonyl group. It serves as a versatile building block in medicinal chemistry due to the trifluoromethyl substituent and the strained cyclopropane ring, which enhance metabolic stability, lipophilicity, and conformational rigidity in drug candidates. Commonly employed in the synthesis of bioactive molecules, including antivirals, antimicrobials, and performance enhancers, especially in the development of pharmaceuticals and agrochemicals where fluorinated and cyclopropyl moieties improve activity and selectivity under mild, precise conditions suitable for late-stage selective synthesis.