N-methoxy-N-methylquinoline-3-carboxamide
98%
Reagent
Code: #215225
CAS Number
215189-85-8
blur_circular Chemical Specifications
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Molecular Information
Weight
216.24 g/mol
Formula
C₁₂H₁₂N₂O₂
thermostat
Physical Properties
Boiling Point
406.9±18.0 °C(Predicted)
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Storage & Handling
Density
1.211±0.06 g/cm3(Predicted)
Storage
Room temperature
description Product Description
N-methoxy-N-methylquinoline-3-carboxamide is a Weinreb amide derivative of quinoline-3-carboxylic acid, widely used as a synthetic intermediate in organic chemistry. It enables the controlled formation of ketones through reaction with organometallic reagents, such as Grignard or organolithium compounds, preventing over-addition that is common with other carbonyl derivatives like esters. This compound is particularly valuable in the synthesis of pharmaceuticals, agrochemicals, and complex bioactive molecules, offering high selectivity and efficiency in multi-step reactions. Its stability and compatibility make it suitable for both solution-phase and solid-phase syntheses.
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