2-((1-Methyl-1H-tetrazol-5-yl)thio)-N-(5-methylisoxazol-3-yl)acetamide

98%

Reagent Code: #192980
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CAS Number 486408-45-1

science Other reagents with same CAS 486408-45-1

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 254.27 g/mol
Formula C₈H₁₀N₆O₂S
inventory_2 Storage & Handling
Density 1.63±0.1 g/cm3(Predicted)
Storage 2-8°C, sealed, dry

description Product Description

Used as a key intermediate in the synthesis of cephalosporin antibiotics, particularly in the production of cefamandole and related beta-lactam antimicrobial agents. Its structure enables effective binding to bacterial cell walls, enhancing the antibiotic's ability to inhibit cell wall synthesis. The tetrazole and isoxazole moieties contribute to improved pharmacokinetics, including better metabolic stability and increased resistance to beta-lactamase enzymes. Commonly employed in pharmaceutical research and development for designing semi-synthetic antibiotics with broad-spectrum activity against both Gram-positive and Gram-negative bacteria.

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Size Availability Unit Price Quantity
inventory 10mg
10-20 days ฿5,180.00
inventory 25mg
10-20 days ฿10,380.00
inventory 100mg
10-20 days ฿19,050.00

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2-((1-Methyl-1H-tetrazol-5-yl)thio)-N-(5-methylisoxazol-3-yl)acetamide
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Used as a key intermediate in the synthesis of cephalosporin antibiotics, particularly in the production of cefamandole and related beta-lactam antimicrobial agents. Its structure enables effective binding to bacterial cell walls, enhancing the antibiotic's ability to inhibit cell wall synthesis. The tetrazole and isoxazole moieties contribute to improved pharmacokinetics, including better metabolic stability and increased resistance to beta-lactamase enzymes. Commonly employed in pharmaceutical research and development for designing semi-synthetic antibiotics with broad-spectrum activity against both Gram-positive and Gram-negative bacteria.
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