2-((1-Methyl-1H-tetrazol-5-yl)thio)-N-(5-methylisoxazol-3-yl)acetamide
98%
Reagent
Code: #192980
CAS Number
486408-45-1
science Other reagents with same CAS 486408-45-1
blur_circular Chemical Specifications
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Molecular Information
Weight
254.27 g/mol
Formula
C₈H₁₀N₆O₂S
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Storage & Handling
Density
1.63±0.1 g/cm3(Predicted)
Storage
2-8°C, sealed, dry
description Product Description
Used as a key intermediate in the synthesis of cephalosporin antibiotics, particularly in the production of cefamandole and related beta-lactam antimicrobial agents. Its structure enables effective binding to bacterial cell walls, enhancing the antibiotic's ability to inhibit cell wall synthesis. The tetrazole and isoxazole moieties contribute to improved pharmacokinetics, including better metabolic stability and increased resistance to beta-lactamase enzymes. Commonly employed in pharmaceutical research and development for designing semi-synthetic antibiotics with broad-spectrum activity against both Gram-positive and Gram-negative bacteria.
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