Used as a key intermediate in the synthesis of pharmaceuticals, particularly in the development of selective enzyme inhibitors and receptor modulators. Its ethynyl group enables click chemistry applications, making it valuable in medicinal chemistry for building complex molecules through coupling reactions. The difluoromethoxy moiety enhances metabolic stability and lipophilicity, which improves drug bioavailability and pharmacokinetic profiles. Commonly employed in the preparation of biologically active compounds, including potential anticancer and anti-inflammatory agents.